BS50 Exam Review 1 - Harvard UniversityThe probability that individual B has the allele goes back to the mating of II-3 and II-4, both of whom are heterozygous. Their child, III-3, has a 2/3 probability of having received the PKU allele and a probability of 1/2 of passing it to IV-2 (B). Therefore, the probability that B has the PKU allele is 2/3 x 1/2 = 1/3.
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